Epigenetic Regulation of Enteric Neurotransmission by Gut Bacteria
نویسندگان
چکیده
منابع مشابه
Epigenetic Regulation of Enteric Neurotransmission by Gut Bacteria
The Human Microbiome Project defined microbial community interactions with the human host, and provided important molecular insight into how epigenetic factors can influence intestinal ecosystems. Given physiological context, changes in gut microbial community structure are increasingly found to associate with alterations in enteric neurotransmission and disease. At present, it is not known whe...
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Specialised cells known as interstitial cells of Cajal (ICCs), distributed in specific locations within the tunica muscularis of the gastrointestinal tract, serve as electrical pacemakers and mediators of enteric neurotransmission. Until recently, evidence to support a functional role of these cells has been, for the most part, indirect. The role of ICCs in pacemaking or neurotransmission has b...
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High throughput methods have increased knowledge about the epigenome and microbiome, and allowed determination of the plausible link between the gut microbiome and epigenetic modification of the host. This has shed light on the development of various diseases such as immune-mediated, metabolic, and cardiovascular diseases, and even cancer. Dysbiosis, imbalanced gut microbiome which is frequentl...
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Biochemical confirmation of salmonellae by conventional tube methods usually requires 2 to 3 days of incubation time preceded by preparation of tubed media and transfer of cultures. The principles of heavy inocula and increased substrate concentrations have been used by Sanders et al. (1) to speed up reaction times and thus reduce the time necessary in the laboratory for analysis. To characteri...
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PURPOSE To investigate the effect of naturally occurring and synthetic peroxides on norepinephrine release from isolated iris-ciliary bodies of several mammalian species. METHODS Hemiirides (bovine) and iris-ciliary bodies (human, rabbit, and rat) were incubated in Krebs solution containing [3H]-norepinephrine ([3H]NE) for 60 minutes. After incubation, tissues were set up for studies of [3H]N...
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ژورنال
عنوان ژورنال: Frontiers in Cellular Neuroscience
سال: 2016
ISSN: 1662-5102
DOI: 10.3389/fncel.2015.00503